Social Wire
Tweeted
Sep 4, 2025
GBinsight Genetic Analysis
@GBHealthWatch 🩺 Highlighted Case Study: High-HDL isn’t always protective: SCARB1 p.Pro376Leu and “hidden” coronary risk Read the full champ.ly/G6Ncr2vL/OM5CbvnzSx This month’s GBinsight case features a patient with LDL-C 140 mg/dL, HDL-C 80 mg/dL and premature CHD. Genomic analysis
GBinsight Genetic Analysis
@GBHealthWatch 🩺 Highlighted Case Study: High-HDL isn’t always protective: SCARB1 p.Pro376Leu and “hidden” coronary risk Read the full champ.ly/G6Ncr2vL/OM5CbvnzSx This month’s GBinsight case features a patient with LDL-C 140 mg/dL, HDL-C 80 mg/dL and premature CHD. Genomic analysis
Tweeted
Sep 3, 2025
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Highlighted Case Study — SCARB1 Loss-of-Function: when “great” HDL-C masks higher atherogenic risk Read the full champ.ly/gFPDVFIV/tEcrxTGY2e High HDL-C (85 mg/dL) looked reassuring—until GBinsight sequencing uncovered a frameshift variant in SCARB1, the gene for the
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Highlighted Case Study — SCARB1 Loss-of-Function: when “great” HDL-C masks higher atherogenic risk Read the full champ.ly/gFPDVFIV/tEcrxTGY2e High HDL-C (85 mg/dL) looked reassuring—until GBinsight sequencing uncovered a frameshift variant in SCARB1, the gene for the
Tweeted
Sep 2, 2025
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Highlight — PPARG-FPLD3 that masqueraded as “familial chylomicronemia” Read the full champ.ly/5jCbZsog/e7YQtVUQPE A middle-aged patient cycling through fibrates and fish-oil for triglycerides >1,500 mg/dL kept crashing back into pancreatitis. GBinsight
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Highlight — PPARG-FPLD3 that masqueraded as “familial chylomicronemia” Read the full champ.ly/5jCbZsog/e7YQtVUQPE A middle-aged patient cycling through fibrates and fish-oil for triglycerides >1,500 mg/dL kept crashing back into pancreatitis. GBinsight
Tweeted
Sep 1, 2025
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Highlight — PPARG Y123C/Y151C + SCARB1 S129L: lipodystrophy that hides behind severe hyper-TG Read the full repochamp.ly/6nc2_ZpPMEoLKNP A patient flagged for triglycerides >1,800 mg/dL, low HDL-C and early-onset diabetes was initially worked-up for
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Highlight — PPARG Y123C/Y151C + SCARB1 S129L: lipodystrophy that hides behind severe hyper-TG Read the full repochamp.ly/6nc2_ZpPMEoLKNP A patient flagged for triglycerides >1,800 mg/dL, low HDL-C and early-onset diabetes was initially worked-up for
Tweeted
Aug 29, 2025
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Spotlight — PPARG Y123C/Y151C + SCARB1 S129L: the lipodystrophy variant pair that masquerades as familial chylomicronemia Read the full repochamp.ly/_rSSaOcrqKLal7x An adult with TG > 2,000 mg/dL, low HDL-C and new-onset diabetes was initially worked-up for
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Spotlight — PPARG Y123C/Y151C + SCARB1 S129L: the lipodystrophy variant pair that masquerades as familial chylomicronemia Read the full repochamp.ly/_rSSaOcrqKLal7x An adult with TG > 2,000 mg/dL, low HDL-C and new-onset diabetes was initially worked-up for
Tweeted
Aug 28, 2025
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Highlighted Case Study — Polygenic hypercholesterolemia revealed by a 98th-percentile LDL-C polygenic risk score (PRS) Read the full repochamp.ly/tObCYmGS0nbNbYS This month’s GBinsight vignette features a patient whose LDL-C sat in the “familial” range, yet sequencing
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Highlighted Case Study — Polygenic hypercholesterolemia revealed by a 98th-percentile LDL-C polygenic risk score (PRS) Read the full repochamp.ly/tObCYmGS0nbNbYS This month’s GBinsight vignette features a patient whose LDL-C sat in the “familial” range, yet sequencing
Tweeted
Aug 27, 2025
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Highlight — NPC1L1 R174H: the sterol-hyperabsorber that turns ezetimibe into a precision tool Read the full repochamp.ly/Jf0W-3hMbnPUhTq A patient with persistently elevated LDL-C despite statin therapy was sequenced with the GBinsight Dyslipidaemia + ASCVD
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Highlight — NPC1L1 R174H: the sterol-hyperabsorber that turns ezetimibe into a precision tool Read the full repochamp.ly/Jf0W-3hMbnPUhTq A patient with persistently elevated LDL-C despite statin therapy was sequenced with the GBinsight Dyslipidaemia + ASCVD
Tweeted
Aug 26, 2025
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Spotlight — NOS3 c.1975del (p.His659ThrfsTer79): a single-allele cut in the nitric-oxide pathway that elevates vascular risk Read the full repochamp.ly/t0PvGZ30pKPAtse A middle-aged patient with drug-resistant hypertension and early coronary calcification
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Spotlight — NOS3 c.1975del (p.His659ThrfsTer79): a single-allele cut in the nitric-oxide pathway that elevates vascular risk Read the full repochamp.ly/t0PvGZ30pKPAtse A middle-aged patient with drug-resistant hypertension and early coronary calcification
Tweeted
Aug 25, 2025
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Spotlight — MC4R p.Loss-of-Function and early-onset severe obesity Read the full repochamp.ly/lWlr8S55I5Cjiyr A child with relentless hyperphagia and BMI > 3 SD above age norms was analysed using the GBinsight Metabolic & Cardiometabolic panel. Sequencing
GBinsight Genetic Analysis
@GBHealthWatch 🧬 Case Study Spotlight — MC4R p.Loss-of-Function and early-onset severe obesity Read the full repochamp.ly/lWlr8S55I5Cjiyr A child with relentless hyperphagia and BMI > 3 SD above age norms was analysed using the GBinsight Metabolic & Cardiometabolic panel. Sequencing
Tweeted
Aug 22, 2025
GBinsight Genetic Analysis
@GBHealthWatch bit.ly/longevity100-i…vSY Your personal longevity health kit, including: • 🔍 Longevity Genetic Index Panel: Discover key genetic markers associated with a longer lifespan. • ❤️ Cardiovascular Health Panel: Assess your genetic
GBinsight Genetic Analysis
@GBHealthWatch bit.ly/longevity100-i…vSY Your personal longevity health kit, including: • 🔍 Longevity Genetic Index Panel: Discover key genetic markers associated with a longer lifespan. • ❤️ Cardiovascular Health Panel: Assess your genetic
